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  Yidong Hu

  Secretary of the Party Committee of Jiangsu Industrial Technology Research Institute, at Deputy Director of the Yangtze River Delta National Technology Innovation Center，

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  Yican Wu

  Academician of the Chinese Academy of Sciences

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  Fawwaz Habbal

  Executive Dean of Harvard University School of Engineering and Applied Sciences

Organ chip is a micro artificial organ grown on microfluidic chip combined the technology of stem cell, regenerative medicine, biomaterials, tissue engineering, microfluidic self-assembly application.
The goal of studying organ chip is to simulate the human tissue environment on the chip, carry out the culture of a variety of cells, tissues and organs, reproduce the organ function on the chip. By controlling the biological behavior of cells in the process of in vitro culture, drug screening and evaluation and the construction of disease model through organ chip will promote basic research for basic medicine. This report shed a light on the progress of organ chips in recent years, including the construction of a two-photon / multiphoton organ chip fast and high-precision printing system with independent intellectual property rights, which solves the problem of cross-scale processing of organ chips; More than ten tissues of organ chip models composed of human cells are made by tissue engineering and micro processing technology and means, which solves some key technical problems in drug screening and disease construction. The artificial intelligence system based on deep learning algorithm with the self-developed high-sensitivity biomedical electronic equipment, an automatic instrument that can accomplish accurate detection and measurement of organ chip, which solves the problems of complex operation for observation and analysis in the use of organ chip. Now cooperated with a number of domestic top three hospitals, the screening of accurate tumor drug sensitivity has completed.

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  Zhongze Gu

  Dean of School of Biomedical Engineering, Southeast University

As one of the core leading technologies of scientific and technological revolution, 3D printing is an important technical means to realize the digital transformation of hospitals, which widely used in the field of digital medical application of orthopedics, oncology, stomatology etc. (Including 3D printing rehabilitation aids, surgical guides, surgical models and implants)
Patients have obvious individual body differences, which challenge the conventional treatment .3D printing technology can provide patients with personalized and accurate treatment through digital measurement, which can solve the contradiction between personalized needs and standardized products. Biological 3D printing is a highest level of 3D printing technology and an extremely important new regenerative medicine engineering technology to reconstructs human tissues and organs, involved the processing of active materials with biomaterials, growth factors and cells.

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  Jinwu Wang

  Chief Physician of Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine

Electronic skin is an important development direction of the future electronic industry, which will bring revolutionary changes to the fields of medical diagnosis and treatment, flexible display, intelligent robot and so on. The great gap in mechanical properties between electronic equipment and biological tissue is the main bottleneck in the development of this kind of devices. The unique intrinsic flexibility, solution processability and structural diversity of organic semiconductor materials make them an important direction in the development of this kind of electronic devices. However, at present, the array density of stretchable transistors is only equivalent to the development level of silicon transistors in the 1960s, which greatly limits the application prospect of a new generation of flexible electronic devices that can realize the functions of biological signal reading, processing, and storage in the construction of intelligent electronic systems. The biggest challenge is the lack of high-resolution patterning and integration methods of universal organic electronic materials. For the first time, we realized full direct lithography patterning of organic conductive, semi-conductive and dielectric materials, broke through the key technical barriers that have long restricted the entry of electronic skin into practical industrial production and application, obtained the highest reported density of stretchable transistor array, and integrated more than 10000 transistors in an area smaller than thumbnail. More than 100 times higher than the previous record. This new technology path will change the paradigm in the manufacturing field of flexible electronic devices industry, and finally bring the revolutionary development of wearable electronics industry.

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  Yuqing Zheng

  Distinguished Researcher, Department of Micro-Nano Electronics, School of Information Science and Technology, Peking University